Name | FISETIN HYDRATE |
Synonyms | Deoxyquercetin FISETIN HYDRATE 5-Deoxyquercetin, 3,3',4',7'-Tetrahydroxyflavone 3,3μ,4μ,7-Tetrahydroxyflavone, 5-Deoxyquercetin, Natural Brown1 4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-,hydrate |
CAS | 345909-34-4 |
EINECS | 208-434-4 |
Molecular Formula | C15H10O6 |
Molar Mass | 286.238 |
Melting Point | >330 °C (lit.) |
BRN | 292829 |
Storage Condition | -20°C |
Physical and Chemical Properties | The luteflavin comes from Rhus succedanea L, a plant of the family sumac, with yellow needle-like crystals (dilute ethanol) and a melting point of 3300°C (decomposition). Soluble in ethanol and almost insoluble in water. |
Hazard Symbols | Xi - Irritant![]() |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
RTECS | LK9250000 |
FLUKA BRAND F CODES | 10 |
Color index | 75620 |
flavonoids | fisetin, also known as fisetin, is a natural flavonoid, it was first isolated and extracted from lacquer tree in 1833. It has antioxidant, anti-inflammatory, anti-tumor, anti-aging and other effects. |
clinical evaluation | fisetin (fisetin,FIT) is a flavonoid yellow needle-like crystalline compound, from the bacalaceae plant tree Toxicodendron sylvetre (Sieb. et Zucc.) O. Extracted from Kuntze, widely distributed in vegetables and fruits. Because of its B ring has a special structure of two phenolic hydroxyl groups, it has strong pharmacological effects, such as anti Virus, treatment of hepatitis Virus; Inhibition of apoptosis, human melanoma, anti-vascular proliferation, nerve protection, anti-cancer and other pharmacological activities. Despite the significant effect of the drug fisetin in the prevention and treatment of diseases, its low water solubility (solubility less than 1 mg/ml), chemical instability, lipid solubility and low dissolution rate, the fast metabolism and other properties limit its pharmaceutical preparation and clinical application. |